From: Lesley Groff <████████████>
Sent: Wednesday, December 4, 2013 4:17 PM
To: Jeffrey Epstein
Subject: Joe Thakuria

from Joe Thakuria...a follow up to his last email...

It's exciting since with the exception of the clinical whole genome =that Illumina has offered for years but at a very low volume due to =ost and very limited clinical indication (for now)), the other stuff =including the clinical exomes) hasn't really even been around beyond a =ear or so. The iPS cell lines would have been something you could only =et from a handful of labs worldwide and, even then, the researchers =ould most likely be prioritizing their own projects - not doing =one-off— individualized cell lines for interested parties.

Anyway, I'll make sure he gets access to the latest and greatest and he =an choose those things that are of the greatest scientific and personal =nterest for him from the list. Maybe along the way also help some of =hese kids with genetic disorders that we haven't been able to =olecularly diagnose through conventional Sanger sequencing at MGH.

Cheers,

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