This document is a research article exploring the bidirectional communication between the immune system and the brain, particularly focusing on its implications for pain management in patients with low-back pain and sciatica. It discusses the role of proinflammatory cytokines in disc degeneration and pain, and reviews current literature on the subject. The article also examines the potential for new therapeutic approaches targeting immune system interactions to improve pain management.
documents/EFTA00308035.pdf
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